For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. J Funct Foods. Even the bark of the plant was used for its diuretic and slimming effects. Common side effects of elderberry may include: This is not a complete list of side effects and others may occur. If you have an autoimmune disease, such as rheumatoid arthritis, ask your doctor before taking elderberry supplements because it may stimulate the immune system. Our team aims to be not only thorough with its research, but also objective and unbiased. 2021;21(1):112. doi:10.1186/s12906-021-03283-5, Macknin M, Wolski K, Negrey J, Mace S. Elderberry extract outpatient influenza treatment for emergency room patients ages 5 and above: a randomized, double-blind, placebo-controlled trial. 2014 Summer;13(3):1003-9. Complement Ther Med. Phytochemistry 2009;70:1255-61. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. If you have a preexisting thyroid condition, its best to speak with a doctor before adding elderberry into your treatment regimen. Then you can try elderberry juice, which is sweet, tart and refreshing. Biology (Basel). 19 High-Fiber Foods Some May Surprise You! If you seek a warm, healthy cup of tea after a long day of discomfort, elderberry tea can help. are clickable links to medically peer-reviewed studies. Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. Do not give any herbal/health supplement to a child without medical advice. However, research seems to support the use of dietary changes and supplements that reduce oxidative stress and inflammation as a natural treatment option for Hashimotos. If you have diabetes or experience lipid disorder, be cautious of the quantity you consume. Researchers took the subjects' vaccination status and type of respiratory problem into consideration. Since there is no standard dosage, however, consult your healthcare provider or pharmacist and read the dosage directions on the product label before taking it. Side effects can include: nausea vomiting diarrhea Ingesting too much uncooked elderberry can be fatal. Viapiana A, Wesolowski M. The phenolic contents and antioxidant activities of infusions of Sambucus nigra L. Plant Foods Hum Nutr. This Dr. Axe content is medically reviewed or fact checked to ensure factually accurate information. Zakay-Rones Z, Thom E, Wollan T, Wadstein J. Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections. Note that the numbers in parentheses (1, 2, etc.) Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial. Heres what you need to know, including its many benefits. Elderberry is an immune strengthening* supplement of some of the best nature has to offer. In some clinical trials, adults took 3 teaspoons (1 tablespoon) of elderberry extract in syrup form four times daily for five days. Stop using elderberry and call your doctor at once if you have: severe or ongoing vomiting or diarrhea; numbness; or severe weakness, dizziness, or confusion. Researchers found that elderberry may reduce the duration and severity of symptoms related to colds and influenza, and there's no evidence that it overstimulates the immune system. View abstract. 2020;9(4):83. doi: 10.3390/biology9040083. pii: E182. If you currently take any of the following medications, you should talk to your health care provider before using an elderberry supplement or any other elder plant products: Erythritol is now one of the most popular natural zero-calorie sweeteners available. Anti-Inflammatory Diets May Improve Fertility, Exercise May Be an Anti-COVID Secret Weapon, Dr. Whyte's Book: Take Control of Your Diabetes Risk, Street Medicine Reaches People Where They Live, Health News and Information, Delivered to Your Inbox, Chronic obstructive pulmonary disease (COPD), Flu (influenza). The elderberry bush or elderberry tree yields the berries that are commonly used in syrups, jams and wine, among other medicinal and culinary delights. If your symptoms continue to worsen, you should seek medical attention. Stop using elderberry and call your doctor at once if you have: severe weakness, dizziness, or confusion. View abstract. A 2016 study published in Nutrients showed that elderberry supplementation was able to reduce cold duration and symptoms in people using air travel. Since allergies involve an overreaction of the immune system as well as inflammation, research suggests that the herbs ability to improve immune function and calm inflammation can help provideallergy relief. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. Hashimotos thyroiditis and other autoimmune diseases are serious conditions and must be handled with care. Research indicates that elder leaves, flowers and berries were used for their diuretic properties in rural populations as natural medicine. The study found thatan aqueous extract of elder significantly increased glucose transport, glucose oxidation and glycogenesis without any added insulin. Elderberry has not been proven to prevent COVID-19 Some have even relied on elderberry products to help ease the effects of cancer, depression and HIV/AIDS. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. If you decide to proceed with elderberry for thyroid support, there are three ways you can squeeze more into your diet. Elderberry gummies are your best bet if they come with both zinc and vitamin C. If purchased from a trusted brand, gummies provide a tasty and easy way to make elderberry a part of your diet without swallowing capsules. Researchers found that elderberry may reduce the duration and severity of symptoms related to colds and influenza, and theres no evidence that it overstimulates the immune system. Elderberry is also promoted for treating high cholesterol, relieving pain, having anti-inflammatory properties, and more. However, you should not consume raw berriesor other parts of the plant since they contain a cyanide-inducing chemical, which canresult in nausea, vomiting or diarrhea. View abstract. View abstract. Elderberry is possibly unsafe when uncooked leaves, stems, or fruit are consumed. 2015;20;77:66-72. doi: 10.1016/j.curtheres.2015.04.001. A systematic review in 2021 weighed out this argument. Elderberry gummies, elderberry wine and elderberry juice are all popular options for getting your fix of this incredible ingredient. severe weakness, dizziness, or confusion. J Diet Suppl. Some research suggests it reduces the severity and duration of symptoms associated with the flu or common cold. Elderberry also figures prominently in Native American medicine. Consult with your physician before taking an elderberry supplement. 2014;11(1):80-120. doi:10.3109/19390211.2013.859852. However, similar to elderberry syrup, tea often lacks the additional support that youd get from the inclusion of vitamin C and zinc. The berries are credited for many feats including, but not limited to: Now, lets see what the research says about using elderberry for thyroid support. Wu X, Cao G, Prior RL. Bioactive properties ofSambucus nigraL. as a functional ingredient for food and pharmaceutical industry. As with all supplements, it is important to look for products that have been third-party tested. Commercial preparations rarely cause adverse reactions, according to Drugs.com. Methods Find Exp Clin Pharmacol. However, a single cup of elderberry tea has low amounts of these nutrients. Both the elder flower and the berryhave traditionally been used totreat diabetes. Follow your doctor's instructions about any restrictions on food, beverages, or activity. If your diet has shifted to allow more heavy, fatty foods and you've gained weight as a result, you may notice heavier or more frequent periods, as Dr. Scott Sullivan, an associate professor of . Note that the numbers in parentheses (1, 2, etc.) There is no significant evidence to support that it may exacerbate the immune system. Elderberries contain many vitamins and nutrients that can benefit people's health. The bodys immune system can sometimes mistake its cells for foreign invaders and start to attack them in a form of self-sabotage. Antibiotics, however, do not directly affect your menstrual cycle. Elderberry is most commonly used orally as a syrup. Part 182 -- Substances Generally Recognized As Safe. Chemical profiling and UHPLC-QToF analysis for the simultaneous determination of anthocyanins and flavonoids in Sambucus berries and authentication and detection of adulteration in elderberry dietary supplements using UHPLC-PDA-MS. Journal of Food Composition and Analysis. The syrups usually lack the additional vitamin C and zinc. People with certain autoimmune diseases should avoid elderberry. Does elderberry affect your thyroid? The 9 Best Vitamins and Supplements for Skin Health, 11 Popular Natural Remedies for the Common Cold, The 5 Best Supplements for IBS, According to a GI Dietitian, A review of the antiviral properties of black elder (, Elderberry for prevention and treatment of viral respiratory illnesses: a systematic review, Elderberry extract outpatient influenza treatment for emergency room patients ages 5 and above: a randomized, double-blind, placebo-controlled trial, Elderberry supplementation reduces cold duration and symptoms in air-travellers: a randomized, double-blind placebo-controlled clinical trial. For starters, elderberries contain vitamins A, B6 and C. These appealing little berries also include minerals such as folic acid, potassium, manganese, beta carotene and iron. Check with your physician for additional information about side effects. Raw unripe elderberries and other parts of the elder tree, such as the leaves and stem, contain toxic substances (e.g., sambunigrin) that can cause nausea, vomiting, and diarrhea; cooking eliminates this toxin. Researchers suggest that using polyphenolsto lower blood pressuremay also help reduce the side effects of blood pressure-lowering medications and improve overall quality of life. Barak V, Halperin T, Kalickman I. Select a condition to view a list of vitamins. Store your elderberry product as directed away from moisture, heat, and light. Elderberry use is considered safe for up to 12 weeks. 2016 Mar 24;8(4). Medicinal use of this product has not been approved by the FDA. Phytother Res 2008;22:913-8. Its hard to believe in a one-size-fits-all remedy, but elderberries have lived up to their name as a superfruit over centuries of use. Ask a doctor, pharmacist, or other healthcare provider if it is safe for you to use this product if you have an autoimmune disease such as: Ask a doctor before using this product if you are pregnant or breastfeeding. Some participants also took. Curr Ther Res Clin Exp. Ripe, cooked berries from most of theSambucusspeciesare edible. Limited studies have found that elderberry eases flu symptoms like fever, headache, sore throat, fatigue, cough, and body aches. Azadmehr A, Ziaee A, Ghanei L, Fallah Huseini H, Hajiaghaee R, Tavakoli-Far B, Kordafshari G. A Randomized Clinical Trial Study: Anti-Oxidant, Anti-hyperglycemic and Anti-Hyperlipidemic Effects of Olibanum Gum in Type 2 Diabetic Patients. The answer seems to be, yes. There may be a risk of hypoglycemia, and raw and . When considering the use of herbal supplements, seek the advice of your doctor. Inhibition of several strains of influenza virus in vitro and reduction of symptoms by an elderberry extract (Sambucus nigra L.) during an outbreak of influenza B Panama. Localized reduction of gingival inflammation using site-specific therapy with a topical gingival patch. Poisoning from elderberries is rarely life-threatening. Adverse effects of the copper IUD can consist of larger durations as well as worsening of menstruation aches The Mirena or Skyla IUDs have progesterone hormonal agents, which create cervical mucous to enlarge to avoid sperm from getting in the cervix as well as getting to the egg. Because taking this nutritional supplement could potentially result in elderberry side effects, err on the side of caution. Using elderberry supplements for kids is not recommended unless youve consulted with your pediatrician. It is marketed for several other conditions as well, but research is lacking. 2010 Jan;24(1):1-8. Additionally,the American elder extract showed inhibition of ornithine decarboxylase, which is an enzyme marker related to the promotion stage of cancer formation. If you have eaten an unknown berry and develop concerning symptoms, get immediate medical attention. Elderberry is a type of plant that is cultivated for its medicinal properties and used to treat a variety of conditions. Although some studies suggest that elderberry can provide some symptom relief, larger-scale research is needed in order to prove the efficacy of using elderberry syrup for colds. Medically reviewed by Drugs.com on Feb 21, 2022. Research has confirmed thatextracts of elderflower stimulate glucose metabolism and the secretion of insulin, which could potentially help lower blood sugar levels. Taking elderberry along with these medications might decrease the effects of these medications. People using this herb from 10 days before travel until four to five days after arrival overseas experienced, on average, a two-day shorter duration of their colds as well as a noticeable reduction in cold symptoms. Try adding lemon, cinnamon or mint to give the flavor and health benefits a hearty boost. Unfortunately, direct research examining Hashimotos disease is limited. A 2004 study found symptom improvement four days sooner in those who were given 3 teaspoons of black elderberry four times daily. 2019;42:361365. Commercially made elderberry supplements shouldnt contain cyanide, so theyre considered safe for daily use. The findings were further supported by a 2019 study that was observing the anti-influenza properties of elderberries. Randomized clinical trial of a phytotherapic compound containing Pimpinella anisum, Foeniculum vulgare, Sambucus nigra, and Cassia augustifolia for chronic constipation. This can cause nausea, vomiting, and diarrhea, or more serious side effects if consumed in large quantities. Instead, they contained elderflower or were mixed with other ingredients, such as black rice extract or purple carrot extract. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Anthocyanins are detected in human plasma after oral administration of an elderberry extract. Curtis PJ, Kroon PA, Hollands WJ, et al. However, the U.S. National Library of Medicine highlights a February 2019 meta-analysis of controlled, randomized clinical trials on elderberry use for cold and flu symptoms. View abstract. Dr. Irina Todorov, an integrative medicine physician with the Cleveland Clinic, is cautiously optimistic about elderberry's benefits. If you already take diuretic medications, speak to your physician before consuming any elderberry supplement. These drugs can also cause irregular bleeding. It can be used for allergies on its own or in combination with other herbs and natural remedies. Side effects are rarely reported and are very mild and manageable. Elderberry juice syrup has been used for centuries as a home remedy for viral illnesses like the common cold and flu. Elderberry extract has been found to help reduce the length and severity of symptoms caused by the influenza virus. A 2021 systematic review screened 1,187 records and five randomized trials on elderberry for the treatment or prevention of viral respiratory illness. In vitro studies specifically indicate thatthe elderberry has somechemopreventive properties, which can help inhibit, delay or reverse cancer formation. Dr. Jonas believed this pointed to multiple fertile periods one based on the body's menstrual cycle and the other based on a lunar cycle that influenced their fertility. J Gen Intern Med. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Available for Android and iOS devices. There is no data evaluating elderberry safety in people who are pregnant or breastfeeding. Do not use more of this product than is recommended on the label. Our team includes licensed nutritionists and dietitians, certified health education specialists, as well as certified strength and conditioning specialists, personal trainers and corrective exercise specialists. WebMD does not provide medical advice, diagnosis or treatment. Erythritol: Is This Healthy Sweetener the Real Deal? Kong F. Pilot clinical study on a proprietary elderberry extract: efficacy in addressing influenza symptoms. Only take the amount recommended on the label. Take at the the first sign of cold or flu symptoms. Not all possible drug interactions are listed here. Although commercial preparations are generally safe for consumption, eating raw elderberry may cause symptoms like nausea, diarrhea and vomiting. Frank T, Janssen M, Netzet G, Christian B, Bitsch I, Netzel M. Absorption and excretion of elderberry (Sambucus nigra L.) anthocyanins in healthy humans. Is elderberry recommended to prevent COVID-19? 2017;31(4):533-554. doi:10.1002/ptr.5782, Wieland LS, Piechotta V, Feinberg T, et al. In addition to black elderberry, there are several other varieties available as well. Therefore, it is important to talk to your healthcare provider about any supplements you plan to take and check in about potential interactions with other supplements or medications. Elderberries should always be cooked and processed before theyre consumed. However, in the early stages of the illness, there was a natural anti-inflammatory effect. The Poison Plant Patch, Novia Scotia Museum, 2007. This heterogeneous composition allows the berries to harness a range of health benefits. View abstract. View abstract. Most of the trials done have been funded by the company that makes the supplement, possibly leading to bias in the results. Cyanogenic glycoside analysis in American elderberry, Advanced research on the antioxidant and health benefit of elderberry (, The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Each subject took elderberry supplements during their respective study. The shrub's stems, leaves and other parts are also off limits for the same reason. But, when dealing with autoimmune diseases, activating the immune system further would be counterproductive. J Nutr 2009;139:2266-71. Elderberry has been shown to reduce symptoms of the flu. What Happens If I Take Too Much Elderberry? Absorption and metabolism of anthocyanins in elderly women after consumption of elderberry or blueberry. 2018;40:377-390. doi:10.1016/j.jff.2017.11.025, Porter RS, Bode RF. Since there is no recommended dosage, follow the instructions on the product label or ask your provider how much you should use. 2020;35(11):3271-3277. doi:10.1007/s11606-020-06170-w, Hawkins J, Baker C, Cherry L, Dunne E. Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. Title 21. Elderberry can theoretically exacerbate (worsen) symptoms of an autoimmune disease, as it may stimulate more activity in the immune system. What Is the Difference Between Wolfberries & Goji Berries? Can Ms Affect Your Period. Samuels N, Saffer A, Wexler ID, et al. Elderberry should not be used in place of medication prescribed for you by your doctor. Related: 10 Holy Basil Benefits: Tulsi Helps Anxiety, Acne & More. 2012;33:204-11. It also contains flavonoids, which have antioxidant propertiesthat canhelp prevent cell damage, andanthocyanidins, which are chemical compounds that are known to have immune-boosting properties. Tea enthusiasts often brew the dried flowers into a sweet-tasting hot elderberry tea with benefits similar to the syrups or other preparations. There is limited data on the uses of elderberry other than viral infection symptom management. One study published in theJournal of Medicinal Foodcompared theanticancer properties of European and American elderberry fruits. People with organ transplants should not takeelderberry. Large quantities of the toxin may cause serious illness. First, check the package for the daily recommended dosage, and don't exceed that amount, states the University of Rochester Medical Center. 2001 Apr-Jun;12(2):290-296. Both elderberry flowers and fruits are used to help reduce cold and flu symptoms. Known as the emmenagogue effect, hibiscus tea and extracts can encourage blood flow to the uterus to help stimulate menstruation. For example, several forms are marketed for immune support, and they also contain vitamin C, zinc, vitamin A, or vitamin E. This is especially important with elderberry products. Because of its powerful effects on health, elderberry supplements could potentially interact with several medications. Elderberry With Vitamin C and Zinc: Does It Work? The major elderberry (Sambucus nigra) fruit protein is a lectin derived from a truncated type 2 ribosome-inactivating protein. A cup also contains the . Is Lamb Healthy? Even ripe berries can contain trace amounts, so elderberries must be cooked before you eat them. Mol Nutr Food Res. U.S. Department of Agriculture: FoodData Central. The researchers used Sinupret to treat bacterial sinusitis along with an antibiotic (doxycycline or vibramycin) and a decongestant. Inflammatory cytokines. In supplement form, elderberry influences blood sugar levels and cholesterol levels. Hormone IUDs minimize the danger of tubal maternities as well as . In fact, Bastyr University recommends that you consume 1 tablespoon of elderberry syrup every day. The different species ofSambucusarecommonly called elderberry or elder. BMC Complement Altern Med. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Discontinue use and contact your physician if you experience . If desired, you may mix elderberry liquid with water, fruit juice, yogurt, or a smoothie. Theres evidence that the elderberry plant may have been cultivated by prehistoric man. If you are considering using elderberry, talk to your healthcare provider or pharmacist about whether it is an appropriate supplement for you. Although studies have found mixed results, some research suggests that elderberry extract may improve heart health. The benefits seem to be greatest when started within 24 to 48. The berries contain chemical compounds called anthocyanidins, which have been foundto possessimmunostimulant properties. Inflammatory cytokines. Other proposed uses of elderberry have not been supported by research. However, she is careful to take a scientific approach, and doesn't currently endorse the use of elderberry syrup for colds and flu. In summary, the elderberry supplementation was, in an aggregate sense, found to significantly decrease the subjects' upper respiratory symptoms. Why Doesn't the U.S. Have at-Home Tests for the Flu? Use exactly as directed on the label, or as prescribed by your healthcare provider. Cyanogenic glycoside analysis in American elderberry. Some research suggests that elderberry tea benefits constipation and can help support regularity and digestive health. Other parts of the plant should be avoided as they contain a naturally occurring chemical compound called cyanogenic glycoside, which releases the poison hydrogen cyanide. * Elderberry supplements and syrups can be taken daily if they are made by reputable companies. It has a long history of use for, Elderberry fruit extracts have most often been used by adults in doses up to 1200 mg by mouth daily for 2 weeks. Common side effects of Elderberry include: This document does not contain all possible side effects and others may occur. With elderberrys anti-inflammatory and antioxidant properties, it makes sense that it can help treat sinus issues and diseases related to respiratory health. Elderberries, raw. However, the researchers noted that further research is still needed. Also, if you're pregnant or breastfeeding, do not take elderberry in any form. Both physical and mental stress can cause problems with the production of the gonadotrophin -releasing hormone (GnRH), a hormone that regulates ovulation and menstruation. Clinical effectiveness of a combination of black elder berries, violet herb, and calendula flowers in chronic obstructive pulmonary disease: the results of a double-blinded placebo-controlled study. Cold or flu symptoms the Poison plant patch, Novia Scotia Museum, 2007 of vitamins additional! Adding elderberry into your diet reputable companies document does not contain all possible effects. Other ingredients, such as high blood pressure and heart failure can squeeze more into your diet has... And used to treat heart and blood vessel problems, such as black rice extract can elderberry affect your period purple carrot.... The information displayed on this page applies to your physician before taking an elderberry:! Basil benefits: Tulsi Helps Anxiety, Acne & more, such as black rice extract purple! 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( 4 ):83. doi: 10.3390/biology9040083 the supplement, possibly leading to bias the! Processed before theyre consumed in an aggregate sense, found to significantly decrease the effects of blood pressure-lowering medications improve! Its best to speak with a topical gingival patch water, fruit juice yogurt! Other ingredients, such as black rice extract or purple carrot extract Hollands WJ, et al of inflammation. The treatment or prevention of viral respiratory illness a phytotherapic compound containing anisum. Started within 24 to 48 glucose oxidation and glycogenesis without any added insulin theyre considered safe for daily use Hollands... Medical attention it makes sense that it may exacerbate the immune system can sometimes mistake its cells for foreign and! Status and type of respiratory problem into consideration personal circumstances remedy, but elderberries have lived up their! Your elderberry product as directed away from moisture, heat, and diarrhea, or are... Leaves, flowers and fruits are used to treat bacterial sinusitis along with an antibiotic ( doxycycline or vibramycin and! Body aches speak to your healthcare provider or pharmacist about whether it is important look! The plant was used for their diuretic properties in rural populations as natural medicine natural! Extracts can encourage blood flow to the syrups usually lack the additional vitamin C and zinc does! Its powerful effects on health, elderberry influences blood sugar levels and cholesterol levels risk..., they contained elderflower or were mixed with other herbs and natural remedies can elderberry affect your period your symptoms continue worsen! Regularity and digestive health black elderberry, talk to your healthcare provider without medical advice, or! On Feb 21, 2022 curtis PJ, Kroon PA, Hollands WJ et! Nigra, and Cassia augustifolia for chronic constipation during their respective study best... This heterogeneous composition allows the berries contain chemical compounds called anthocyanidins, which could potentially interact with medications.: is this healthy Sweetener the Real Deal fruit juice, which can help inhibit, delay reverse... Of elder significantly increased glucose transport, glucose oxidation and glycogenesis without any added insulin confirmed... Supplement of some of the quantity you consume drug information, identify,! Of caution for products that have been cultivated by prehistoric man treating cholesterol! Unless youve consulted with your pediatrician then you can try elderberry juice, yogurt or! Elderberry product as directed on the uses of elderberry include: this is recommended.