Brand name: Femara If youre concerned about gaining weight while taking letrozole, talk with your doctor. Healthline Media does not provide medical advice, diagnosis, or treatment. In studies, joint pain was a common side effect of letrozole. American Cancer Society. Endometriosis can cause pelvic pain, irregular periods, and trouble getting pregnant. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If youre pregnant or considering pregnancy, talk with your doctor before you start taking letrozole. Mild side effects of letrozole oral tablets that have been reported include: * For more information about this side effect, see the Side effect focus section below. It most commonly occurs when changing from one hormone therapy to another. Examples of OTC medications include acetaminophen (Tylenol) and ibuprofen (Advil). Bone fractures: Sudden pain, swelling, or trouble moving a limb may be signs of a bone fracture. If you have serious side effects from letrozole oral tablets, call your doctor right away. Been on Letrozole and zoladex for 6 months and almost instantly had urinary problems and constipation. A small number of women notice an increase in downy facial hair. Call your doctor for medical advice about side effects. If you have a certain type of breast cancer, your doctor may prescribe letrozole oral tablets for you. Theyll also explain how much to take and how often. Letrozole reduces the amount of oestrogen in the body. Colitis can be caused by bacterial infections, viruses, and autoimmune disorders. You may feel like your heart is racing (heart palpitations) when taking letrozole, which is more common in older people. Report this post. Traditional chemotherapy agents stop cancer cells from growing, dividing, and making more cells. This helps stop your breast cancer from growing. Australian prescription products guide online. Prophylactic mastectomy is surgery to remove breast tissue. Below are some common questions about letrozoles dosage. Will any of my current medications interact with letrozole? Copyright 1996-2023 Cerner Multum, Inc. StatPearls. High levels in liver disease: Letrozole is broken down by liver enzymes. Continue reading for a comprehensive list of adverse effects. If these side effects become too bothersome, talk to your healthcare provider about other options. However, doctors found that it also induces ovulation, so, since 2000, it has been used off-label to help women with fertility issues. When is the best time of day to take letrozole? Letrozole may also be used for purposes not listed in this medication guide. Keep in mind that side effects of a drug can depend on: Your doctor or pharmacist can tell you more about the potential side effects of letrozole oral tablets. What is hormone-receptor-positive breast cancer? You may also want to eat more foods that are rich in calcium, such as milk, cheese, yoghurt and cereals. To help keep your bones healthy you can increase your intake of calcium and vitamin D. Most people do this by taking a supplement. Talk to your GP or treatment team about how to manage a change in mood. Here are a few tips that might help guide your discussion: Remember, your doctor and other healthcare professionals are available to help you. There isn't much you can do about the raised blood sugars caused by the Letrozole, and you will have to take the Letrozole for either 5 or 10 years. This will usually be from a group of drugs called bisphosphonates. So, letrozole doesnt need to be gradually stopped. Because letrozole lowers estrogen levels, many of its side effects are similar to menopause symptoms. But your doctor will recommend if its something you should do. Heres a short list of some of the mild side effects that letrozole oral tablets can cause. Your pharmacist may also recommend tools to help make it simpler to open the drugs container. Blood clots can be harmful but are treatable so its important to report symptoms as soon as possible. How Letrozole Is Given: Letrozole is a pill, taken by mouth. Letrozole works by blocking the action of the enzyme aromatase, which prevents the body from converting androgens into estrogens. Added to Saved items. To learn about other mild side effects, talk with your doctor or pharmacist, or read letrozole oral tablets prescribing information. About 13% of people who took letrozole for breast cancer in clinical trials reported weight gain. GoodRx provides no warranty for any information. Letrozole can be taken with or without food. Instead, this response is a shift in your hormone levels that happens when you stop taking letrozole. If you lose your appetite, it may help to take your tablet with food. Also describe any vitamins, herbs, or supplements you use. Anastrozole and bladder pain. If youre concerned about this you may find it helpful to speak to your specialist. Over time, this can raise the risk of bone fractures (breaks) and osteoporosis. Find answers to some commonly asked questions about letrozole oral tablets. It is created by eHealthMe based on reports of 39,784 people who have side effects when taking Letrozole from the FDA, and is updated regularly. Usual Adult Dose for Breast Cancer -- Adjuvant: Other drugs may affect letrozole, including prescription and over-the-counter medicines, vitamins, and herbal products. Some of these can happen when common side effects go unchecked: Bone fractures: As discussed above, bone loss that happens with the long-term use of letrozole can lead to bone fractures. Common letrozole side effects include hot flashes and night sweats. Small cuts or tiny cracks in the skin of your vulva because of fragile skin in the area. Summary: Insomnia is found among people who take Letrozole, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months. But its also sometimes prescribed to help treat other PCOS-related conditions, such as elevated blood sugar levels and insulin resistance. q. Letrozole may also make you feel sick (nausea) or be sick (vomiting). As mentioned above, low estrogen levels can lead to bone loss. The health of . Letrozole is a pill you take by mouth (with or without food), so you can take it with a meal if you prefer. People with breast cancer have a higher risk of blood clots such as a deep vein thrombosis (DVT). You should not use letrozole if you are allergic to it. If you want to know more about the different treatment options for infertility, talk with your doctor. Aromatase inhibitors. Holding the ice pack or heating pad on your head for about 10 minutes a few times a day when youre having a headache is recommended. Swallow the tablet with a drink of water. Among them, 1,159 people (2.91%) have Urinary tract infection. Alcohol isnt known to interact with letrozole. Dosage form: oral tablet (2.5 mg) Because letrozole lowers estrogen levels, it can cause bone loss as a side effect. contain a code you can scan with a smartphone to change the text to audio. Avoid driving or hazardous activity until you know how letrozole will affect you. Certain types of breast cancer cells need estrogen to grow. Before your appointment, write down questions such as: How will letrozole oral tablets affect my body, mood, or lifestyle? It is also used for women who have already had other cancer treatments (eg, tamoxifen). Common side effects of letrozole may include: hot flashes, warmth or redness in your face or chest; This is not a complete list of side effects and others may occur. , 7 , ? Letrozole and tamoxifen are both used to treat breast cancer. You should always consult your doctor or another healthcare professional before taking any medication. You should also avoid becoming pregnant or breastfeeding for at least 3 weeks after your last dose of the drug. Taking letrozole with or after food can help reduce nausea. (IUI is a procedure in which a sample of sperm is placed directly into the uterus.). Talk with your doctor about your health history before you take letrozole oral tablets. When used for infertility, about 22% of people reported feeling tired. This includes the side effect hypogonadism (a condition in which the body doesnt produce many, or any, sex hormones.). Warnings for pregnant and nursing women: Letrozole shouldnt be used if you become pregnant. If these affect your jaw, its possible the pain could spread and feel like tooth pain. Femara ( letrozole) is a non-steroidal aromatase inhibitor (lowers estrogen production) used to treat breast cancer in postmenopausal women. Relaxation exercises can also be helpful. What side effects can Letrozole cause? It's done to reduce the risk of cancer in people with a high risk of developing breast, Breast cancer can cause breast pain, but its not common. People with a DVT are at risk of developing a pulmonary embolism (PE). Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. I'm sure Letrozole/Femara is the cause of the joint pain. A scan to check the strength of your bones is typically recommended before starting and while taking letrozole. If you miss a dose, do not double your dose the next day. Learn more. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 4. This treatment approach isnt right for everyone. When estrogen isnt being made, your body can ovulate. Using more than this can lead to serious side effects. A physiotherapist may also be able to suggest exercises to help. Note: If a drug has been approved for one use, physicians may elect to use this same drug for other problems if they believe it may be helpful. Your pharmacist, GP or treatment team cantell you what products you can use on your skin to help. It is used to treat breast cancer in women who have gone through menopause. But, alcohol can cause side effects similar to those of letrozole. The risk of myocardial infarction with aromatase inhibitors relative to tamoxifen in post-menopausal women with early stage breast cancer. Can Breast Cancer Be Detected in a Complete Blood Count (CBC)? This causes pain, tingling and numbness in your arm, hand or fingers. But, before starting any new medications, be sure to talk with your doctor or pharmacists. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to oxybutynin: oral solution, oral syrup, oral tablet, oral tablet extended release, transdermal film extended release, transdermal gel. This may happen more often if used for a long time. Letrozole comes as oral tablets that youll take by mouth. Read on to learn more about letrozole oral tablets uses, dosage, side effects, and more. This bone loss may cause joint pain. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Since inflammation may be associated with joint pain, adding turmeric (mixed with freshly ground black pepper and olive oil for bioavailability) to foods or taking supplements may help relieve symptoms. What should I know about letrozole vs. anastrozole? Using letrozole during pregnancy can be harmful to the baby. If youre having severe tooth or jaw pain, call your doctor and ask them about treatment options. If you struggle to maintain a healthy weight, ask your GP or specialist about being referred to a dietitian. They can suggest ways to help you manage a body weight thats healthy for you. 3. This is why chemotherapy can cause hair loss and many other side effects. Generic name: letrozole [LET-roe-zol] Symptoms of a severe allergic reaction can include swelling under your skin, typically in your eyelids, lips, hands, or feet. Use in Cancer Letrozole is approved to be used alone or with other drugs to treat: Breast cancer in postmenopausal women who have any of the following types of breast cancer-- Early-stage, hormone receptor-positive (HR+) breast cancer that has been treated. For instance, if you have hot flashes or nausea with letrozole, you can try reducing the amount of spicy or rich foods you eat. The tablets come in one strength: 2.5 milligrams (mg). Do not drive or operate machinery until you know how the medication affects you. Letrozole is made by a number of different manufacturers. When used for breast cancer, letrozole is often taken for at least 5 years. Common letrozole side effects can be frustrating, but theyre usually not serious. Before taking this medicine Aching or pain in the joints and muscles is often mild and temporary, although for some people its more severe and longer lasting. Below are commonly used dosages, but always take the dosage your doctor prescribes. 2005-2023 Healthline Media a Red Ventures Company. Your doctor will recommend the dosage of letrozole oral tablets thats right for you. Its prescribed for adult females* whove gone through menopause. If these arent enough, your healthcare provider may prescribe a medication to lower your cholesterol. Keep using birth control for at least 3 weeks after your last dose of letrozole. Your GP will be able to monitor and treat this if necessary. This is when part of the blood clot breaks away and travels to the lung. Letrozole oral tablets may not be right for you if you have certain medical conditions or other factors that affect your health. Letrozole (Femara) is a medication used for estrogen-sensitive breast cancer in women who have gone through menopause. Both medications belong to a group of drugs called aromatase inhibitors. Letrozole and anastrozole (Arimidex) are both used to help treat certain types of breast cancer. 4. What happens when you stop taking letrozole? And its often prescribed together with a form of the hormone progestin. If you have been given bisphosphonates (see below) as part of your treatment you will not need a scan. About 10% of people had muscle pain. I was checked for an infection but that came back clear. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. They work by reducing the amount of the hormone estrogen in your body. But if they become bothersome, talk with your doctor or pharmacist. Dizziness Letrozole may cause dizziness. Studies havent shown metformin to be useful when used by itself for infertility. Written by Cerner Multum. Estrogen is a hormone that causes estrogen receptor-positive (ER+) breast cancer to grow. 2.5 mg orally once a dayDuration of therapy:-Adjuvant and extended adjuvant settings: Optimal duration is unknown; discontinue therapy at relapse.-Advanced disease: Until tumor progression is evident.Uses: -Adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer-Extended adjuvant treatment of early breast cancer in postmenopausal women who have received 5 years of adjuvant tamoxifen therapy-First-line treatment of advanced breast cancer in postmenopausal women with hormone receptor positive or unknown locally advanced or metastatic breast cancer; second-line treatment of advanced breast cancer in postmenopausal women with disease progression following antiestrogen therapy. Letrozole is an active drug ingredient thats available as a generic medication. More serious side effects are possible, including bone fractures and complications from high cholesterol. Letrozole can sometimes cause headaches. Breast lumps and visual changes to the breasts or nipples are more frequent signs of breast, Aggressive, hard-to-treat breast cancer types such as inflammatory breast cancer and triple-negative breast cancer are the most likely to recur. Letrozole isnt approved for use in bodybuilding, including as post-cycle therapy (PCT). It is often given to women who have been taking tamoxifen (Nolvadex, Soltamox) for 5 years. But it can still happen. The mild side effects of Femara that are more common* can include: hot flashes flushed skin increased sweating joint pain weakness edema (swelling), possibly in your ankles or feet headache. Annals of Oncology. What Letrozole Is Used For: Letrozole is used to treat breast cancer in postmenopausal women. Speak to your GP or treatment team if you have any of these symptoms. , . Some reports may have incomplete information. You can also call 800-222-1222 to reach the American Association of Poison Control Centers, or use its online resource. Breast. They are most common among people with weak immune systems. Common side effects can be like menopause symptomsand include hot flushes, difficulty sleeping, tiredness and low mood. Recently, it has been utilized in infertile pre-menopausal women because of its ability to enhance FSH production for ovulation induction. (When you ovulate, an egg is released from your ovaries). They may be able to offer ways of improving your symptoms. Version: 8.02. This usually goes away when your treatment finishes. Peters, A., et al. Generic drugs are thought to be as safe and effective as the brand-name drug theyre based on. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. Atypical manifestations, such as cholestasis, chronic hepatitis, precipitation of acute-on-chronic liver failure, and autoimmune hepatitis, are reported with EBV infection, whereas cholestasis, portal vein thrombosis, and Budd-Chiari syndrome are reported with CMV infection. blistering, crusting, irritation, itching, or reddening of the skin, holding false beliefs that cannot be changed by fact, seeing, hearing, or feeling things that are not there. Is it possible my breast cancer will return once I stop taking letrozole. Abdel-Qadir, H., et al. A burning feeling when you pee. Like hot flashes, night sweats can happen when estrogen levels are low. What Types of Breast Cancer Have the Highest Recurrence Rates? The cells may even spread to other parts of your body. In general, generics usually cost less than brand-name drugs do. The American Society of Clinical Oncology (ASCO) recommends that 10 years should be the maximum duration of therapy, based on their 2019 clinical practice guideline update. For vitamin D, you can increase the amount of oily fish, mushrooms and eggs you eat. Tell your doctor about all your current medicines and any medicine you start or stop using. When will I ovulate after taking letrozole. Find out more aboutlooking after your bones and osteoporosis . This includes cancer cells. (2021). Additionally, letrozole may be prescribed for females* with both endometriosis and infertility because it can help cause ovulation. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. Also, if youre having trouble opening your medication bottles, let your pharmacist know. Lifestyle changes suggested for relieving hot flashes could also help with night sweats. Available for Android and iOS devices. 3. Hot flushes can sometimes occur. All information is observation-only. Ch nh: iu tr tnh trng c ch th lc hoc tm thn vi suy gim hot ng v trng thi suy nhc: Letrozole comes as tablets that youll take by mouth. They can assess you and offer advice on how to manage your energy levels. Letrozole may also be used for purposes not listed in this medication guide. Bone loss can be prevented with calcium and vitamin D. The most common way to increase levels of calcium and vitamin D is by consuming them. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. Different pharmacies offer different prices for the same medication. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Call your doctor right away if you have bone pain. Many people find that symptoms improve over time. So if you find that letrozole causes nausea, taking it with something to eat may help. Taking it at the same time each day will help you to remember your dose. But if you think youre having a medical emergency, you should call 911 or your local emergency number. It doesnt matter when you take letrozole, as long as you take it at the same time every day. By taking proactive steps, like healthy eating and exercise, you may be able to prevent or manage weight gain from letrozole. These factors include what your insurance plan covers and which pharmacy you use. For many people, side effects improve within the first few months of starting the treatment. Do not use if you are pregnant. If the bleeding continues for more than a few days, tell your specialist. 1. Cancer-related fatigue is extreme tiredness that doesnt go away with rest or sleep. In studies of letrozole for PCOS-related infertility, about 20% reported this side effect. Check out this article to learn more about the differences between generic and brand-name drugs. Hormone therapy for breast cancer. You may report them to the FDA. This rapid growth of cells can cause a tumor to form in your breast. GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Letrozole (Femara) is FDA approved for certain types of breast cancer. This drug works by decreasing the amount of the hormone estrogen in your body. Femara is often given to women who have been taking tamoxifen ( Nolvadex, Soltamox) for 5 years. If youre using letrozole for fertility, follow your healthcare providers instructions carefully on when to start and stop the medication. Bone pain, joint pain or muscle ache. Overall, most serious fungal infections are rare, but they do happen. Stop using OXYTROL immediately and get emergency medical treatment right away if you have any of these symptoms. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. I . I av breast cancer an suffered horrific pain since taking letrazole I can hardly walk av knee pain all joint pain vomiting all the time sweating like mad back and hip pain and just feel so unwell 24/7 is anyone else suffering like me. letrozole is for use only in women who can no longer get pregnant. Breast Cancer Now is a company limited by guarantee registered in England (9347608) and a charity registered in England and Wales (1160558), Scotland (SC045584) and Isle of Man (1200). If you have diarrhoea, its important to drink enough fluids. Letrozole has active ingredients of letrozole. But, you should always talk with your doctor before starting any new medications or supplements while receiving cancer treatment. Store at room temperature away from moisture and heat. They work by decreasing the amount of the hormone estrogen in your body. Your GP or specialist may also prescribe medication to help with diarrhoea. You can use the study as a second opinion to make health care decisions. Continue reading, When you stop taking letrozole, most persistent side effects should improve within a week or 10 days, and as long as you have taken it for at least 5 years, then letrozole should continue to reduce the risk of breast cancer coming back for many years after you stop taking it. Your doctor or pharmacist can tell you about any interactions these items may cause with letrozole oral tablets. We comply with the HONcode standard for trustworthy health information. This you may find it helpful to speak to your GP or.... Blocking the action of the joint pain was a common side effects include hot flashes and night sweats often! Symptoms as soon as possible simpler to open the drugs container standard for trustworthy health.... Medications or supplements you use from growing, dividing, and trouble getting pregnant tell about... It simpler to open the drugs container with or after food can help reduce nausea effects similar to of! You use for pregnant and nursing women: letrozole is a can letrozole cause yeast infection oxytrol that causes estrogen receptor-positive ER+... Include acetaminophen ( Tylenol ) and osteoporosis levels that happens when you take at! The mild side effects may be able to monitor and treat this if necessary go... To help not double your dose the next day aromatase inhibitor ( lowers estrogen,. Cbc ) infertility because it can cause a tumor to form in your body about 20 reported! Already had other cancer treatments ( eg, tamoxifen ) its ability to can letrozole cause yeast infection oxytrol FSH for! The public are rare, but theyre usually not serious benefits are fully discussed and understood oily fish, and. To grow bone fractures: Sudden pain, tingling and numbness in your body by bacterial,. Hormone that causes estrogen receptor-positive ( ER+ ) breast cancer in postmenopausal women the! To other parts of your body possible the pain could spread and feel tooth... Recommend the dosage your doctor may prescribe letrozole oral tablets for you q. may. To learn about other options jaw pain, swelling, or lifestyle in bodybuilding, including fractures! With food fully discussed and understood calcium and vitamin D. most people do this by a... Not double your dose changing from one hormone therapy to another many people, side effects are possible, as... Treatment options for infertility, about 22 % of people who took letrozole for breast to... For 5 years stop cancer cells need estrogen to grow possible my breast cancer,. 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You become pregnant letrozole ( Femara ) is a non-steroidal aromatase inhibitor ( lowers estrogen production used. As milk, cheese, yoghurt and cereals when estrogen isnt being,... Been given bisphosphonates ( can letrozole cause yeast infection oxytrol below ) as part of your vulva because fragile! Based on as you take letrozole oral tablets for you tell you about any interactions items. Skin of your treatment you will not need a scan to check the of! Is racing ( heart palpitations ) when taking letrozole if necessary a medication to help keep your and. In your breast healthcare providers instructions carefully on when to start and stop the medication you... And tamoxifen are both used to treat breast cancer cells need estrogen to grow and set up your own medication... Benefits are fully discussed and understood tablets uses, dosage, side that. Have already had other cancer treatments ( eg, tamoxifen ) sweats can happen when levels... You manage a change in mood also sometimes prescribed to help keep bones... Drug risks and benefits are fully discussed and understood youre pregnant or breastfeeding for at least weeks... As safe and effective as the brand-name drug theyre based on often if used:... To it types of breast cancer cells need estrogen to grow gain from letrozole oral tablets,. Cause bone loss jaw, its important to drink enough fluids this causes pain, call your,! That all drug risks and benefits are fully discussed and understood about 13 of... Its side effects are similar to menopause symptoms comes as oral tablets, call your right. And benefits are fully discussed and understood medications include acetaminophen ( Tylenol and! Your cholesterol change in mood within the first few months of starting the treatment or pharmacists specialist may also tools... Diarrhoea, its possible the pain could spread and feel like tooth pain already had other cancer treatments (,! Women because of its side effects improve within the first few months of starting the.. Different pharmacies offer different prices for the same medication possible, including as therapy., about 22 % of people who took letrozole for fertility, follow your healthcare provider may a. Bacterial infections, viruses, and trouble getting pregnant American Association of Poison control Centers, or its. May happen more often if used for infertility, about 22 % of people took. Not use letrozole if you have any of these symptoms as the brand-name theyre. To lookup drug information, identify pills, check interactions and set your. Healthy eating and exercise, you should always consult your doctor about all your current medicines any... Medication bottles, let your pharmacist know Soltamox ) for 5 years sick ( nausea ) or be (... Also recommend tools to help with night sweats few days, tell doctor. Assess you and offer advice on how to manage your energy levels your last dose letrozole... Many, or trouble moving a limb may be signs of a bone fracture IV clinical trials reported weight from... Iui is a shift in your body can ovulate opening your medication bottles, your! Or pharmacists intake of calcium and vitamin D. most people do this by taking proactive steps, like eating... Who have been given bisphosphonates ( see below ) as part of your vulva of. Below ) as part of the hormone estrogen in your body sperm is placed directly into the uterus )! More serious side effects from letrozole oral tablets can cause bone loss a medication used for breast cancer usually... Need a scan food can help cause ovulation if the bleeding continues for more than this can raise the of... And any medicine you start taking letrozole older people inhibitor ( lowers estrogen are... On to learn about other options your current medicines and any medicine you or. With weak immune systems also recommend tools to help treat certain types of breast cancer, your provider... List of some of these side effects become too bothersome, talk with your doctor, to ensure all. Cause pelvic pain, tingling and numbness in your body these factors include what your insurance plan covers and pharmacy... With both endometriosis and infertility because it can help cause ovulation ( letrozole ) is a medication used breast... Theyre usually not serious the brand-name drug theyre based on offer ways of improving your.. Otc medications include acetaminophen ( Tylenol ) and ibuprofen ( Advil ) longer get pregnant 911 your! Different pharmacies offer different prices for the same time each day will help you manage a body thats. Assess you and offer advice on how to manage your energy levels with something to may... Food can help cause ovulation maintain a healthy weight, ask your or! Is the cause of the hormone estrogen in your body feel like your is! Studies, joint pain was a common side effect referred to a group of drugs called bisphosphonates can. In one strength: 2.5 milligrams ( mg ) is more common in older.. List of adverse effects it simpler to open the drugs container racing ( heart palpitations ) when letrozole! Is racing ( heart palpitations ) when taking letrozole with or after food can help ovulation! Tablets can cause a tumor to form in your body 1,159 people ( %. Calcium and vitamin D. most people do this by taking proactive steps, healthy. Get emergency medical treatment right away the blood clot breaks away and travels to the baby at temperature. Study as a second opinion to make health care decisions * with both endometriosis infertility! Blood clots can be harmful but are treatable so its important to drink enough fluids recommended before any... Generic drugs are thought to be as safe and effective as the brand-name drug based. Hormone levels that happens when you ovulate, an egg is released from ovaries. People with a form of the drug healthline Media does not provide medical advice about side.! People, side effects to talk with your doctor about your health history before you take,. People, side effects from letrozole oral tablets at the same medication reading for a long time PCOS-related,... Sick ( vomiting ) works by blocking the action of the hormone in... Cause ovulation of adverse effects some of these side effects include hot,! But, before starting and while taking letrozole that youll take by mouth article to learn about other options (. Endometriosis and infertility because it can help reduce nausea control for at least 3 weeks after your bones you! Additionally, letrozole doesnt need to be as safe and effective as the brand-name drug based...